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Meningococcal disease, prophylaxis
Adult: As N. meningitidis serogroup B vaccine (recombinant, adsorbed): Bexsero 2 doses of 0.5 mL given at least 1 mth apart. Trumenba 2 doses of 0.5 mL given at 6 mth interval; or 3 doses of 0.5 mL w/ the 1st 2 doses at least 1 mth apart followed by a 3rd dose at least 4 mth after the 2nd dose. As N. meningitidis serogroup C or ACWY conjugate vaccine (conjugated to diphtheria CRM197 or tetanus toxoid carrier protein): Single dose of 0.5 mL.
Child: As N. meningitidis serogroup B vaccine (recombinant, adsorbed): Bexsero 2-5 mth 3 doses of 0.5 mL at least 1 mth apart. Booster dose of 0.5 mL is given between 12-15 mth or not later than 24 mth of age; 6-11 mth (unvaccinated) 2 doses of 0.5 mL given at least 2 mth apart. Booster dose of 0.5 mL is given at 2 yr of age, w/ at least 2 mth interval from the primary series; 12-23 mth (unvaccinated) 2 doses of 0.5 mL given at least 2 mth apart. Booster dose of 0.5 mL is given 12-23 mth apart from the primary series; 2-10 yr 2 doses of 0.5 mL given at least 2 mth apart; ≥11 yr Same as adult dose. Trumenba ≥10 yr Same as adult dose. As N. meningitidis serogroup C vaccine (conjugated to diphtheria CRM197 protein): 2-12 mth 2 doses of 0.5 mL given at least 2 mth apart. Booster dose may be given based on national recommendations; >12 mth Same as adult dose. As N. meningitidis serogroup C vaccine (conjugated to tetanus toxoid carrier protein): 2-4 mth 2 doses of 0.5 mL given at least 2 mth apart. Booster dose of 0.5 mL is given at 12-13 mth of age w/ an interval of 6 mth after the last vaccination; >4 mth Same as adult dose. As N. meningitidis serogroup ACWY vaccine (conjugated to diphtheria CRM197 protein): ≥2 yr Same as adult dose. Booster dose of 0.5 mL may be given based on national recommendations. As N. meningitidis serogroup ACWY vaccine (conjugated to tetanus toxoid carrier protein): 6 wk to 12 mth 2 doses of 0.5 mL given at least 2 mth apart. Booster dose of 0.5 mL is given at 12 mth of age; >12 mth Same as adult dose. Booster dose of 0.5 mL may be given based on national recommendations.
Child: As N. meningitidis serogroup B vaccine (recombinant, adsorbed): Bexsero 2-5 mth 3 doses of 0.5 mL at least 1 mth apart. Booster dose of 0.5 mL is given between 12-15 mth or not later than 24 mth of age; 6-11 mth (unvaccinated) 2 doses of 0.5 mL given at least 2 mth apart. Booster dose of 0.5 mL is given at 2 yr of age, w/ at least 2 mth interval from the primary series; 12-23 mth (unvaccinated) 2 doses of 0.5 mL given at least 2 mth apart. Booster dose of 0.5 mL is given 12-23 mth apart from the primary series; 2-10 yr 2 doses of 0.5 mL given at least 2 mth apart; ≥11 yr Same as adult dose. Trumenba ≥10 yr Same as adult dose. As N. meningitidis serogroup C vaccine (conjugated to diphtheria CRM197 protein): 2-12 mth 2 doses of 0.5 mL given at least 2 mth apart. Booster dose may be given based on national recommendations; >12 mth Same as adult dose. As N. meningitidis serogroup C vaccine (conjugated to tetanus toxoid carrier protein): 2-4 mth 2 doses of 0.5 mL given at least 2 mth apart. Booster dose of 0.5 mL is given at 12-13 mth of age w/ an interval of 6 mth after the last vaccination; >4 mth Same as adult dose. As N. meningitidis serogroup ACWY vaccine (conjugated to diphtheria CRM197 protein): ≥2 yr Same as adult dose. Booster dose of 0.5 mL may be given based on national recommendations. As N. meningitidis serogroup ACWY vaccine (conjugated to tetanus toxoid carrier protein): 6 wk to 12 mth 2 doses of 0.5 mL given at least 2 mth apart. Booster dose of 0.5 mL is given at 12 mth of age; >12 mth Same as adult dose. Booster dose of 0.5 mL may be given based on national recommendations.
Subcutaneous
Meningococcal disease, prophylaxis
Adult: As unconjugated N. meningitidis serogroup ACWY vaccine: Single dose of 0.5 mL.
Child: As unconjugated N. meningitidis serogroup ACWY vaccine: ≥2 yr Same as adult dose.
Child: As unconjugated N. meningitidis serogroup ACWY vaccine: ≥2 yr Same as adult dose.
